Recombinant antigen K39 for Leishmania infantum
The protein K39 is a repetitive immunodominant epitope in a kinesin-related protein that is highly conserved among viscerotropic Leishmania species. It has been described that a rK39 ELISA is sensitive and specific for serodiagnosis of human and canine VL.
Recombinant antigen for the diagnosis of Leishmaniasis caused by Leishmania infantum, a human and animal infectious disease (mainly dogs and cats).
| SKU | Source | Applications | In-house validation | Details |
|---|---|---|---|---|
RAG0061
 |
E. coli | WB, DB, IE, DE, CLIA, LF | ELISA |
|
| RAG0061BIOT (biotinylated) | E. coli | WB, DB, CE, DAS, NP, PO | ELISA |
|
Top product (Satisfaction guarantee)* under availability, for liquid format
For research and comercial use IVD only (*)
(*) Our IVD reagents are provided for research and commercial use in vitro: not for human in vivo or therapeutic use. You can get more information about the general features and about the shipping, storage, defrost, manipulation and stability of all of our reagents. In addition, we follow a rigorous quality control for each lot.
Bact to list of Recombinant antigens for infectious diseases
How to reconsitute lyophizated vials
Recombinant antigens for the diagnosis of Leishmaniasis
List of citations
- Abass E., Bollig N., Reinhard K., et al. (2013) rKLO8, a novel Leishmania donovani - derived recombinant immunodominant protein for sensitive detection of visceral leishmaniasis in Sudan. PLoS neglected tropical diseases, vol. 7,7 e2322.
- Mollett G., Bremer Hinckel B.C., Bhattacharyya T., et al. (2019) Detection of Immunoglobulin G1 Against rK39 Improves Monitoring of Treatment Outcomes in Visceral Leishmaniasis. Clin Infect Dis, 69(7):1130-1135.
- Medeiros F.A.C., Souza Filho J.A., Barbosa J.R., Donato L.E., Figueiredo F.B,. Werneck G.L., Paz G.F., Thompson M., Marcelino A.P. (2021) Phase II validation study of the rK39 ELISA prototype for the diagnosis of canine visceral leishmaniasis in Brazil. Cad Saude Publica. 37(3):e00041320.