Hepatitis B virus core protein (HBcAg) is a crucial serology marker of hepatitis B infection and patient follow-up. It is a 21-kDa protein with the intrinsic capacity to self-assemble as a capsid-like particle. It is a nuclear protein that self-assembles during viral replication in liver cells to form a regular 20-hedron structure. It is observed with great frequency in immunosuppressed patients with chronic hepatitis. A good An anti-HBc is important in the identification of HBV-infected individuals who are negative for hepatitis B surface antigen (HBsAg), but are positive for anti-HBc, in an effort to prevent the contamination of blood transfusion products with HBV.
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Bact to list of Recombinant antigens for infectious diseases