Congenital infections (TORCH)

TORCH is the acronym used to describe a group of infectious diseases that are transmitted from the mother to the fetus during pregnancy, known as congenital infections. The acronyms correspond to the initials in English of Toxoplasmosis, Others - such as syphilis, AIDS, EBV, chickenpox, etc. -, Rubella, Cytomegalovirus and Herpes simplex. The high fetal and neonatal morbidity and mortality, and the presence of important sequelae, make congenital infection a major public health problem. Therefore, its prevention, diagnosis, monitoring and treatment are necessary, before, during and after pregnancy.

The transmission of these diseases can occur mainly through the placenta or through direct contact with the microorganism in the birth canal. In rare cases, it can be transmitted through genitourinary infections or invasive procedures during pregnancy. As prevention universal immunization of the population is used, detection during pregnancy of these diseases through serological tests, immunization of the pregnant woman with inactive virus vaccines, and avoiding possible contagion situations during pregnancy. The diagnosis of this panel of diseases is made through a group of tests on both pregnant women, the fetus, and the newborn. A blood sample is taken from the pregnant woman to detect antibodies against these diseases. A blood sample is taken from the fetus through the umbilical cord (cordocentesis) to identify antibodies, or a sample of amniotic fluid is taken (amniocentesis) to detect the pathogen. During pregnancy, ultrasound scans are done to determine if there is any alteration that could be due to a congenital disease. At birth, if congenital infection is suspected, a culture of placental tissue is performed. And finally, a blood sample is taken from the newborn, usually from the heel, to detect antibodies against these diseases. For clinical diagnosis of neurological complications, ultrasound, computed tomography or magnetic resonance imaging is used.

Rekom Biotech offers a wide range of IVD reagents for in vitro diagnosis of infectious diseases (human and animal). We have both recombinant antigens and polyclonal antibodies. Take a look at our portfolio and don't hesitate to contact us! We will be happy to help you.

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BACT TO LIST OF INFECTIOUS DISEASES

Below, you can find the list of congenital infections (TORCH) for which we offer IVD reagents. If you want to know more about a specific disease, and/or consult the IVD reagents that we offer for a certain disease, do not hesitate to take a look.

Acquired immunodeficiency syndrome (AIDS) caused by Human immunodeficiency virus (HIV)

Cytomegalovirus infection (CMV)

Genital herpes caused by Herpes simplex virus type 2 (HSV-2)

Oral herpes caused by Herpes simplex virus type 1 (HSV-1)

Syphilis caused by Treponema pallidum

Toxoplasmosis caused by Toxoplasma gondii