S1 (CTD) is a C-terminal recombinant region of spike glycoprotein S1 ectodomain for SARS-CoV detection. The spike (S) protein is a surface trimer glycoprotein located on the envelope of the virions. It is cleaved into S1 and S2 subunits. The S1 subunit is responsible for host-receptor binding while the S2 subunit contains the membrane-fusion machinery. There are two domains in coronavirus S1, N-terminal domain (S1-NTD) and C-terminal domain (S1-CTD). One or both of these S1 domains potentially bind receptors and function as the receptor-binding domain (RBD).
FOR RESEARCH AND COMERCIAL USE IVD ONLY (*)
(*) Our antigens are provided for research and commercial use in vitro: not for human in vivo or therapeutic use. For more information about the general features of our antigens, you can visit here.